Thanks!
I've been able to do some more playing with this setup, and even took it all over to the studio for an afternoon of some crankin' and some mic'in. (The drummer who was supposed to also be there for full-band comparisons never turned up. Apparently, he stayed up way too late partying the night before and spent the entire next day as a

in his bed.)

Oh well.
One of a few things we found were that the 2x15 wasn't quite as loud as the 4x12. The Sensitivity specs are fairly close, but there's only 2 15"s compared to 4 12"s.
Celestion Fullback 15" Celestion Seventy/80 12"100 watts each (x2) 80 watts each (x4)
99 dB 98 dB
65-4000Hz 80-5000Hz
It could be the actual surface area of the cones that come into consideration as well. Assuming the cones are flat (of course they are not) and actually 12" or 15" in diameter simply just for ease of math formulas and comparisons reveals another side of the experiment. Using the formula Area = π x r2 for each speaker multiplied by number of speakers means:
The 4x12 has approx. 452 sq in. of speaker cone to transmit sound.
The 2x15 has approx. 353 sq in. of speaker cone to transmit sound.
How much this comparison actually impacts the overall loudness could be debatable, but it must mean
something and probably should be considered if planning your own speaker cab build. Don't know about everyone else, but I'll pick sound Quality over sound Quantity at this point in my journey.
The difference in the sound level between the 2 cabs wasn't enormous, but was definitely noticeable that the 2x15 wasn't quite as loud as the 4x12. I felt this to be an advantage, actually. It meant that if you were using an amp that had to be turned up a bit more than what is practical to get into a "sweet spot" you could do so easier without overpowering the room and everyone in it.
For mic testing, we achieved optimum mic levels at a very reasonable and manageable volume; higher than "bedroom" volume and lower than "earplugs mandatory" volume (provided of course that you weren't standing directly in line with the speakers). My guitar used here had B Standard tuning. Both cabs were side-by-side on the floor plugged into my Peavey JSX head, and a sound barrier was placed between the cabs. One sm57 was used at each cab, and a single tube mic captured the room; each mic had it's own Track. The Playback results were interesting, as you could definitely hear the volume difference. Solo'ing each track made me think both cabs sound great by themselves, but together sounded absolutely KILLER once the Levels were more evenly matched! I was very very pleased with the results, and the studio operator was getting a kick out of it too. The Dry Clean sounds continued to be just as killer as I ever wanted them to be. After the mic tests, I ran the amp up quite a bit louder and even changed to a Drop A tuning but everything stayed solid and true without much fuss. I could get a bit of "growl" from the 15"s if I wanted but without damaging anything. The 12"s didn't want to "growl" btw, they just "screamed" more. I didn't use my MP-2 in this session because since I've already decided that my ADA stuff will stay home from now on, I didn't see a point in bringing it for this session. But believe me, I'll still use it at home because I'm always experimenting with stuff there.
Everyone has their own idea of what sounds best to them, and I am hesitant to say this one is "best" for me because while it sure is now, that could change next week, next month, next year... Such is Life.
I should also mention that this 2x15 cab feels slightly lighter in weight than my 4x12. I didn't have a scale to weigh them on for an exact number, but I can note that each Fullback 15" speaker weighs 10.6 lbs (4.8kg) according to Celestion's website, while each Seventy 80 12" speaker weighs 6.8 lbs (3.1 kg). Ugh. More math. So the 2x15 cab then has 21.2 lbs (9.6 kg) of driver weight inside it while the 4x12 cab has 27.2 lbs (12.4 kg) of drivers in it to keep it from floating away.

Again, not a huge difference but a noticeable one.
So there you have it. I'm really happy I finally got the chance to do this, and am very pleased with the results. I believe these are the cabs I will keep. The other 2 4x12 cabs are getting sold, as I do not need 2 full stacks

in my house! Looks cool though, right? lol If I ever get back to playing out again, and only need one cab for that I'll more than likely bring the 2x15.
Would I trade my 2x15 for another 4x12? No.
Would I trade my 4x12 to build another 2x15? I definitely "might" do that.