Some devices have everything internal fully insulated from ground, with only the earth pin in the power cable acting as ground.
This is the preferred way of ensuring single-point grounding, in order to avoid ground-loop [hum], because the builder can now use ordinary jack cables, and arrange single-point grounding for each device at the common mains summing point.
Other devices have their in/out jacks grounded to chassis.
This not preferable, as there's the possibility of ending up with grounding through both the mains prong and simultaneously through the signal cables - because of the chassis-grounded in/out jacks.
As Kim said, the builder can start with simply mounting and connecting the whole shebang, and see if all is ok.
If hum is present:
* either disconnect everything, and then reconnect one device at a time, until hum appears.
* or, disconnect devices one by one until the disappears.
Hum most often develops when using, say, external processors in send/return loops, simply due too signal cables carrying ground in a loop-structure, while this external device is also being grounded through the mains prong.
When the hum-hum device has been found, a usual remedy is to isolate it from the rack rails using insulated bolts and washers and maybe a strip of gaffer on the rails to avoid chassis contact.
Sometime it's possible to use custom signal cables having the ground flex connected at only one end - best option is to leave the open-ground end of the cable connected at the Send jack.