First, my main Rhythm/Lead patch:
Room EQ always at 0% (Full)
MESA RECTO GASM
Voice 7 Warm Hi Gain
Drive 85
OD 70
Master 79
Lo +10
Mid -2
Hi 0
Pres +4
100Hz +10
170 +2
280 0
470 +6
800 -2
1.3 0
2.2 0
3.8 +4
6.3 0
Doesn't sound as "woofy" and loose as these settings might imply, rather it has a very solid fump for me.
UPDATE: I've been trying out a different speaker cab and this main patch really is too woofy after all. My old speakers must have been really holding back all that low end, because the speakers I'm using atm (rebranded Eminence Legend speakers) seem to be a lot more open and neutral sounding than the Celestion/Eminence speaker combo. Therefore, I basically have to write a new patch and start the whole EQ process at 0. And...it sounds pretty good there, too. lol